The Thermo Neptune is a high-resolution multicollector inductively-coupled plasma mass spectrometer. Our Neptune has a NeptunePlus Upgrade, consisting of a large interface pump and a Jet-cone interface for increased sensitivity. The instrument is equipped with nine Faraday cup detectors (eight are moveable), an axial discrete dynode secondary electron multiplier (SEM) with RPQ for high abundance-sensitivity measurements. In addition, we have a multiple-ion counting system consisting of two discrete-dynode SEM ion counter, mounted at the outermost positions in the multicollector array (L4 and H4). For liquid sample introduction into the mass spectrometer a quartz glass double Scott/Cyclon spray chamber, a PFA double Scott/Cyclon spray chamber, or a ESI Apex IR + Spiro membrane desolvator is available. For solid sampling a UV femtosecond laser ablation system can be coupled with the Neptune. Our Neptune is currently used for isotope measurements of Li, Mg, Si, Fe, Rb and Sr (stable and radiogenic).